- Sample Presentation (continued)
- The Article (continued)
- End points:
- Primary endpoint
- Secondary endpoint
- Results (may use tables from the article)
- Author's Conclusions
- The strong points of the methodology were... The weak points of the methodology were...
- Editorial Comments and Letters to the Editor were...
- The conclusions we can legitimately draw from this study are that although the study achieved
statistical significance for decreased mortality in males, the NNT suggests that some patients or
physicians may not believe that the results are clinically significant. Treatment plans should be
individualized based upon discussion with an informed patient. Treatment decisions should also be
limited to those patients who are typical of the patients in this study; that is middle-aged male
patients at high risk who already have clinical coronary disease. The study shows strong evidence
that once coronary disease is established in men, aggressive lipid lowering improves overall mortality
in men. This study does not show the same benefit in women. Attention should be paid to all risk factors
in considering the most appropriate approach. Although some women may wish to pursue lipid lowering, they
should be aware that the data do not show overall benefit in terms of survival.
- The ideal study: This study was well designed. However, future studies might include more women and a longer follow-up.
