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EBM Guidebook

Table of Contents

    Title Page
  1. Introduction
  2. STEP 1: Formulating the Question
    1. POEM
    2. PICO
  3. STEP 2: Finding the Best Evidence
  4. STEP 3: Appraising the Evidence
    1. CAMeL General Steps
    2. CAMeL Critical Appraisal Protocols
      1. Therapy
      2. Diagnostic Tests
      3. Review Articles
      4. Screening Tests
      5. Prognosis
      6. Causation
  5. STEP 4: Preparing an EBM Presentation
    1. Protocol for the Presentation
    2. Sample Presentation
  6. Overview of Statistics
    1. Statistics Without Statistics
    2. Ten Ways to Cheat
  7. Glossary of Terms
    Terms marked with an asterisk (*)
    are defined in the Glossary.
  8. References
Back to Informatics & EBM Instruction page  Back to Evidence-Based Instruction page

VI.  Overview of Statistics  (continued)

  1. Statistics Without Statistics: Did They Use the Right Test?  (continued)
ANOVA (Analysis of Variance)
An ANOVA table is a "super t-test". An ANOVA can test several means of several categories at once. Commonly this test can be seen with stratified data in several groups. Imagine a categorical variable with 4 values (group I, II, III, IV) each with the continuous variable SBP. The ANOVA can test the differences in the 4 categories and look for significance among the means. Perhaps groups I and IV are significantly different but I and III are not. ANOVA's are commonly seen in the larger studies or meta analyses because of their ability to look at several means at once.
 
Correlation
Another very common statistical test is the correlation. Several types exist but the Pearson correlation is usually used. This test involves two continuous variables plotted against each other two generate a new line. The desire is to find some type of association between the two variables in order to build an argument for one variable changing with another variable. The associations are positive or negative or none and range from a perfect -1 to a perfect +1. Strength of association is described by the r-value. Note the slope itself is not significant other than positive or negative. It is inappropriate to use the actual line to describe the effect of one continuous variable on another. Correlations find associations, regressions find equations.
 
Regression
Regression analysis is one of the fundamental pillars of statistics. The actual math of a regression can be quite tedious but the general idea is fairly easy to understand. A regression also looks for significant differences, but also looks at the actual interplay between variables. With regressions authors can build strong arguments that variables interact or "explain" each other. (The F-value is the usual measure of strength of a model.) The principle is based on the equation y = mx + b.
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