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EBM Guidebook

Table of Contents

    Title Page
  1. Introduction
  2. STEP 1: Formulating the Question
    1. POEM
    2. PICO
  3. STEP 2: Finding the Best Evidence
  4. STEP 3: Appraising the Evidence
    1. CAMeL General Steps
    2. CAMeL Critical Appraisal Protocols
      1. Therapy
      2. Diagnostic Tests
      3. Review Articles
      4. Screening Tests
      5. Prognosis
      6. Causation
  5. STEP 4: Preparing an EBM Presentation
    1. Protocol for the Presentation
    2. Sample Presentation
  6. Overview of Statistics
    1. Statistics Without Statistics
    2. Ten Ways to Cheat
  7. Glossary of Terms
    Terms marked with an asterisk (*)
    are defined in the Glossary.
  8. References
Back to Informatics & EBM Instruction page  Back to Evidence-Based Instruction page

II.  STEP 1: Formulating the Question  (continued)

  1. POEM  (continued)
    As clinicians, our most fundamental questions center on diagnosis, prognosis, or therapy in individual patients. The acronym POEM (Patient Oriented Evidence that Matters) suggests that questions are most relevant when they relate to specific patients or clearly identified groups of patients.
  1. PICO
    To build your final question (the question that you will try to answer), focus on the following steps:
  1. Describe your own patient in as much relevant detail as you can:   In a 54 year old white male with new onset of paroxysmal atrial fibrillation and a large left atrium
  2. Describe what you want to answer or ask about your specific patient:   would anticoagulation with warfarin
  3. Describe the comparison or the alternative:   as opposed to no therapy at all
  4. Describe your goal or desired outcome:   reduce the risk of embolic stroke or reduce mortality?
    This is called a PICO question: Patient Intervention Control Outcome.
     
    When you have addressed these issues, write out the question. Writing will force you to be more explicit. Pay special attention to the outcome. Lowering cholesterol is not the same as preventing heart attacks. Pick an outcome that is relevant to your patient.
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