Evidence-Based Course-Integrated Instruction

Course Level: Pediatric Neonatology Fellows -- 2012

EBM Session I Class Materials:  

• Introduction to Evidence-Based Neonatology Lecture Slides
• Use this PICO table to search PubMed
• Study Design
• EBM Worksheet I
  

EBM Session II Class Materials:

• Finding the Best Available Evidence in Neonatology -- Lecture Slides
• NICHD Cochrane Neonatal Systematic Reviews
• Sample scenarios, searches, completed worksheets and CATs for Neonatal Medicine
• EBM Worksheet II
• Assigned Clinical Questions


• EBM Tools: Understanding Biostatics
  
  • Numbers needed to treat (NNT) and Numbers needed to harm (NNH)
  • Relatively Risk Reduction (RRR) and Absolute Risk Reduction (ARR)
    
  • Confidence Intervals (CI)
  • What are Confidence Intervals?
  • Basic & Clinical Biostatistics, 4e.  Beth Dawson, Robert G. Trapp

• Critical Appraisal Tools and Worksheets
  • All-Purpose 2x2 Table Analyser
  • Stats Calculator
  • Odds Ratio to NNT Convertor
  • EBM Pyramid
  • Therapy
  • Diagnosis
  • Harm
  • Prognosis
  • Systematic Review (of Therapy)
  • Clinical Practice Guidelines

EBM Session III Class Materials: 

• Overview of EBM Process Using the Exercise Questions

1. McGuire W, Fowlie PW, Soll RF.  What has the Cochrane collaboration ever done for newborn infants? Arch Dis Child Fetal Neonatal Ed. 2010 Jan;95(1):F2-6. Epub 2009 May 3. PMID: 19414431
2. Polin RA, Lorenz JM, Bateman DA.  Evidence-based neonatology.  NeoReviews, 2006 Sep;7(9):e474-4. 
3. Sinclair JC.  Evidence-based therapy in neonatology: distilling the evidence and applying it in practice. Acta Paediatr. 2004 Sep;93(9):1146-52. PMID: 15384873

Session Resources:

• UCI SOM EBM Guidebook
• How to read a paper (BMJ article series)